ea0009p121 | Endocrine tumours and neoplasia | BES2005
Adma P
, Heald A
, Kane J
, Gibson C
, Davis J
, Buckler H
, Fowler H
Clinic based studies have shown that patients with Addison's disease have relatively high rates of depression and anxiety symptoms compared with population-based reference samples. Addison's disease results in deficiency of dehydroepiandrosterone (DHEA) and DHEA-sulphate in addition to glucocorticoids and mineralocorticoids. DHEA is thought to have beneficial effects on energy level and mood, independent of circulating testosterone levels. Thus there may be a direct link betwe...